RAD140 Powder


Our company is the largest API manufacturer of RAD140 Powder in China.Our production of RAD140 has a history of 3 years, and all production RAD140 raw materials have a purity of more than 99% and each batch has HPLC and NMR detection reports.The mk677 monthly output is 20kg and the quality is stable.
The RAD140 powder produced by our company is mainly supplied to Canada and its European market, and the customer feedback is good. Our company is a leading supplier of health care products, research institutes and fitness enthusiasts.
The RAD140 provided by our company is powder, the color is white , the standard package is 1 kg/aluminum foil bag.We also can be divided into smaller package for the customer.The order is unlimited.After customers purchase, they can be directly processed into tablets and liquids.

It would be the best choice to cooperate with us,due to we have below advantages:
1. Professional.We has developed and produced sram series for 5 years.Rich experience in production, stable product quality, product purity up to 99%.
2. Formal business.Our company can provide HPLC, nuclear magnetic and other professional detection map for each batch of products.
3. Fast delivery. Products will send out within 24hours,delivery time is 7-10days.
4. Good service. We will provide the most thoughtful service, from procurement, quality inspection, delivery to application, etc.

RAD140 Powder product information
RAD140 (Testolone)
Last updated Feb 15, 2018  8
Chemical Name: 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile
Other Name(s): RAD 140, Testolone
Molecular Name: C20H16ClN5O2
Half Life: 12-18 hours depending on individual
RAD 140, also known as Testolone, is an orally bioavailable, non-steroidal, selective androgen receptor modulator (SARM) that has the ability to increase lean muscle mass and reinforce the effects of testosterone without the unwanted side effects of anabolic steroids.
Early studies and user reviews have delivered better results than steroid use with minimal side effects, making it one of the most exciting and powerful SARMs to date. Read on for a comprehensive review of everything you need to know about RAD 140, including benefits, side effects, studies and results for increasing muscle mass and preserving gains.
Benefits

RAD140 powder quality proof(NMR and HPLC)
NMR(2018.4.2)
HPLC(2018.5.18)
RAD140 User Review
RAD140 powder helps increase muscle mass
The number one benefit of supplementing with RAD140 powder is its ability to increase lean tissue without increasing fat. In fact, during initial studies done on monkeys, scientists observed an average weight gain of more than 10% in just 28 days. This was done using only RAD 140 and without any adverse side effects traditionally related to testosterone.
Want to work out longer, harder and get better results every time you hit the gym? Reports of enhanced speed, stamina and endurance during workouts are common when supplementing with Testolone. Additionally, thanks to its ability to increase lean muscle tissue and decrease fat, high-intensity workouts and interval training can be optimized every time.
Similar to other SARMs such as LGD4033 (Ligandrol) or S4 (Andarine), RAD140 produces similar results to testosterone but without the side effects.
When taken in conjunction with anabolic steroids, initial studies indicated that RAD140 reduces the side effects of testosterone stimulation on the prostate and seminal vesicles of monkeys .
Initial studies on mice have found that low doses of RAD140 is all that’s needed to stimulate muscle growth without affecting the weight of the prostate.
RAD140 indirectly reduces body fat by increasing muscle and bone cells, which are more metabolically expensive to maintain than fat cells. By increasing muscle mass, in increase in the metabolism is seen, which results in easier weight loss.
RAD140 was discovered and is currently being developed by pharmaceutical company Radius specifically for the treatment of Androgen Receptor (AR) and Estrogen Receptor Positive (ER+) breast cancer in postmenopausal women.
As testosterone levels in men decline, the risk of disease in androgen-responsive tissue (including the brain) increases, implicating the development of neurodegenerative diseases such as Alzheimer’s Disease.

RAD140  History
RAD140 is currently being developed by pharmaceutical company Radius. Its initial discovery was originally published in 2010, which means studies are limited. However, initial studies, company reports and anecdotal user reviews have been highly promising for building muscle without the side effects of anabolic steroids.
Discovered via an Internal Discovery Program, Testolone is actually being developed for the treatment of breast cancer and muscle wasting in postmenopausal women. According to the company’s website, the FDA accepted their Investigational New Drug Application and the first human clinical trial was expected to begin in 2017.

How RAD140 Works
The androgen receptor (AR) primarily targets normal human sexual development, but its activation by compounds (such as testosterone) also effects bone, muscle, liver and the central nervous system.
The problem within the medical and bodybuilding communities is that using testosterone to activate AR signaling for increased muscle and bone development also affects the sex tissues, resulting in testicular atrophy, enlarged clitoris in females and even risks of prostate cancer. [1]
RAD140, a nonsteroidal selective androgen receptor modulator (SARM) bypasses this issue. Due to the way RAD140 binds to the androgen receptor, different cells respond by releasing different proteins, with only some androgen receptors being activated throughout the body.
This stimulation results in androgen receptor activation in bone and muscle cell, rather than raising liver enzymes or affecting sexual tissue.
According to the Cambridge-based pharmaceuticals company Radius:
“…The potent, orally bioavailable and nonsteroidal RAD 140 is designed to make the hormonal receptors in the tissues of the body act as if they’re getting a good dose of testosterone, setting off the same effects of prohormones and anabolic steroids minus the unwanted side effects…”
There are 8 primary benefits that have been observed in both initial studies and user-reported reviews.
User Review
2. RAD140 may enhance speed, stamina and endurance during high-intensity workouts
3. RAD140 has a greater anabolic effect than testosterone
RAD140 interacts with the hormonal receptors of muscle and bone tissue in the same ways as larger doses of testosterone, all without the estrogenic side effects caused by anabolic steroids.
Many users on forums also report greater anabolic effects than testosterone and is sometimes used as a PCT for steroid users to retain muscle mass between cycles.
4. RAD140 may reduce the side effects of testosterone
Additionally, many anabolic steroid users report concerns for the health of their liver. However, during the 28-day trial these monkeys also showed minimal liver enzyme elevations on a dose 10x higher than the fully effective dose, even though weight was gained during a short timeframe (which can cause liver strain).
Our advice? With the results from RAD140 already proving better than anabolic steroid use, users may be better off forgetting testosterone altogether and sticking to SARMs.
5. Testolone does not appear to have the same side effects of anabolic steroids on reproductive organs
This means that RAD140 has the ability to selectively stimulate muscle and bone growth while reducing the effects on sex tissue such as the prostate or clitoris. (So yes, this means RAD140 is safe for women)
6. RAD140 may aid weight loss by increasing fat loss
Users also report increased muscle growth and decreased fat stores thanks to RAD140’s ability to increase stamina, endurance and speed during a interval training.
7. RAD140 is being trialed for the treatment of breast cancer
In vitro studies completed in 2017 showed that RAD140 inhibited the growth of AR/ER+ breast cancer cells. Results from these studies supported further investigation of RAD140 as a breast cancer treatment, and the first human clinical trials were brought forward [4].
8. RAD140 is indicated to be neuroprotective for brain health in neurodegenerative diseases
However, treating AR diseases with testosterone may increase the risk of prostate cancer. Recent studies suggest that RAD140 may be as effective as testosterone in reducing cell death without side effects to the prostate. 

RAD140 Side Effects
As with most SARMs, studies show that RAD140 does not appear to have any side effects common to steroidal compounds. Unlike testosterone, RAD140 does not cause prostate enlargement or testicular shrinkage.
However, as it is still in early developmental stages, this does not mean that there are no long-term effects. Some user-reported side effects include headaches or insomnia that disappear with correct dosage.
Dosing Recommendations
Testolone studies are still being produced, but it has been known to have equal potency and effectiveness to that of LGD4033.
Studies on male primates suggest 20-30mg per day every 24-36 hours is optimal for maximum skeletal hypertrophy, inline with anecdotal testimonials from users. Safe durations for research have been tolerated for up to 12 weeks, however, developing trials may indicate tolerance for up to 24 weeks.
It is important to note that RAD140 systematically regulates the neuroexcitatory amino acid Kainate which activates glutamate receptors in the brain. Kainate acid’s role in neuronal cell death (specifically in the hippocampus) has been shown to be a primary contributor to Alzheimer’s disease. RAD140 has demonstrated positive results in the prevention of Kainate acid production and medical based research published by The Endocrine Society suggests RAD140 can improve brain health through neuroprotective properties in as little as 13 days (Jayaraman, 2014).
Although safe for women, lower doses ARE recommended. Females are advised to start at 5mg per day with an upper limit of no more than 10mg per day.
As an orally bioavailable compound, RAD140 is available as a liquid to be taken directly and followed with a glass of water.
Although there is no official human dose for RAD140, its potency and effectiveness has been compared to LGD4033.
Current research indicates that it is tolerated for use up to 12 weeks.
Stacking
Although great on its own, RAD140 can be stacked with other SARMs for added benefits tailored to your individual needs.
Many users report stacking RAD140 (Testolone) with MK677 (Nutrobal) and MK2866 (Ostarine) to provide a powerhouse for building muscle, burning fat, boosting growth hormones, joint recovery and improved sleep.
Testolone is particularly beneficial for older users who benefit from reduced muscle wastage, joint health and better sleep for recovery.
Dosages:
RAD140 (Testolone) – 30mg
Looking for the ultimate SARM stack? KONG provides a well-rounded selection of SARMs chosen to work synergistically.
Take the hassle (and cost) out of purchasing your SARMs separately –
KONG is a 5 SARM stack that contains 6mg of RAD140, as well as GW 501516, MK 2866, MK 677, and LGD 4033. RAD160 History
RAD140 is currently being developed by pharmaceutical company Radius. Its initial discovery was originally published in 2010, which means studies are limited. However, initial studies, company reports and anecdotal user reviews have been highly promising for building muscle without the side effects of anabolic steroids.
Discovered via an Internal Discovery Program, Testolone is actually being developed for the treatment of breast cancer and muscle wasting in postmenopausal women. According to the company’s website, the FDA accepted their Investigational New Drug Application and the first human clinical trial was expected to begin in 2017.

How RAD140 Works
The androgen receptor (AR) primarily targets normal human sexual development, but its activation by compounds (such as testosterone) also effects bone, muscle, liver and the central nervous system.
The problem within the medical and bodybuilding communities is that using testosterone to activate AR signaling for increased muscle and bone development also affects the sex tissues, resulting in testicular atrophy, enlarged clitoris in females and even risks of prostate cancer. [1]
RAD140, a nonsteroidal selective androgen receptor modulator (SARM) bypasses this issue. Due to the way RAD140 binds to the androgen receptor, different cells respond by releasing different proteins, with only some androgen receptors being activated throughout the body.
This stimulation results in androgen receptor activation in bone and muscle cell, rather than raising liver enzymes or affecting sexual tissue.
According to the Cambridge-based pharmaceuticals company Radius:
“…The potent, orally bioavailable and nonsteroidal RAD 140 is designed to make the hormonal receptors in the tissues of the body act as if they’re getting a good dose of testosterone, setting off the same effects of prohormones and anabolic steroids minus the unwanted side effects…”
There are 8 primary benefits that have been observed in both initial studies and user-reported reviews.

RAD140 User Review
1. RAD140 may enhance speed, stamina and endurance during high-intensity workouts
2. RAD140 has a greater anabolic effect than testosterone
RAD140 interacts with the hormonal receptors of muscle and bone tissue in the same ways as larger doses of testosterone, all without the estrogenic side effects caused by anabolic steroids.
Many users on forums also report greater anabolic effects than testosterone and is sometimes used as a PCT for steroid users to retain muscle mass between cycles.
3. RAD140 may reduce the side effects of testosterone
Additionally, many anabolic steroid users report concerns for the health of their liver. However, during the 28-day trial these monkeys also showed minimal liver enzyme elevations on a dose 10x higher than the fully effective dose, even though weight was gained during a short timeframe (which can cause liver strain).
Our advice? With the results from RAD140 already proving better than anabolic steroid use, users may be better off forgetting testosterone altogether and sticking to SARMs.
4. Testolone does not appear to have the same side effects of anabolic steroids on reproductive organs
This means that RAD140 has the ability to selectively stimulate muscle and bone growth while reducing the effects on sex tissue such as the prostate or clitoris. (So yes, this means RAD140 is safe for women)
5. RAD140 may aid weight loss by increasing fat loss
Users also report increased muscle growth and decreased fat stores thanks to RAD140’s ability to increase stamina, endurance and speed during a interval training.
6. RAD140 is being trialed for the treatment of breast cancer
In vitro studies completed in 2017 showed that RAD140 inhibited the growth of AR/ER+ breast cancer cells. Results from these studies supported further investigation of RAD140 as a breast cancer treatment, and the first human clinical trials were brought forward [4].
7. RAD140 is indicated to be neuroprotective for brain health in neurodegenerative diseases
However, treating AR diseases with testosterone may increase the risk of prostate cancer. Recent studies suggest that RAD140 may be as effective as testosterone in reducing cell death without side effects to the prostate. 
Side Effects
As with most SARMs, studies show that RAD140 does not appear to have any side effects common to steroidal compounds. Unlike testosterone, RAD140 does not cause prostate enlargement or testicular shrinkage.
However, as it is still in early developmental stages, this does not mean that there are no long-term effects. Some user-reported side effects include headaches or insomnia that disappear with correct dosage.
RAD140 Dosing Recommendations
Testolone studies are still being produced, but it has been known to have equal potency and effectiveness to that of LGD4033.
Studies on male primates suggest 20-30mg per day every 24-36 hours is optimal for maximum skeletal hypertrophy, inline with anecdotal testimonials from users. Safe durations for research have been tolerated for up to 12 weeks, however, developing trials may indicate tolerance for up to 24 weeks.
It is important to note that RAD140 systematically regulates the neuroexcitatory amino acid Kainate which activates glutamate receptors in the brain. Kainate acid’s role in neuronal cell death (specifically in the hippocampus) has been shown to be a primary contributor to Alzheimer’s disease. RAD140 has demonstrated positive results in the prevention of Kainate acid production and medical based research published by The Endocrine Society suggests RAD140 can improve brain health through neuroprotective properties in as little as 13 days (Jayaraman, 2014).
Although safe for women, lower doses ARE recommended. Females are advised to start at 5mg per day with an upper limit of no more than 10mg per day.
As an orally bioavailable compound, RAD140 is available as a liquid to be taken directly and followed with a glass of water.
Although there is no official human dose for RAD140, its potency and effectiveness has been compared to LGD4033.
Current research indicates that it is tolerated for use up to 12 weeks.
Stacking
Although great on its own, RAD140 can be stacked with other SARMs for added benefits tailored to your individual needs.
Many users report stacking RAD140 (Testolone) with MK677 (Nutrobal) and MK2866 (Ostarine) to provide a powerhouse for building muscle, burning fat, boosting growth hormones, joint recovery and improved sleep.
Testolone is particularly beneficial for older users who benefit from reduced muscle wastage, joint health and better sleep for recovery.


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